Now: The little historic, perpetually up-and-coming neighborhood that could. The last neighborhood before the San Francisco world ends at the eastern industrial band and bay. The Dogpatch epicenter is 22nd Street at 3rd Street.
Then: San Francisco's origins as a seaport involved industry and shipbuilding, much of which was centered in this area. The homes were designed as dwellings for workers, some of whom built their own homes. Many of these buildings, dating back to the 1860s, survived 1906 earthquake and fire and stand today.
How To Get There: The Muni T-line runs down Third Street, and the 20th Street station is one (double-length) block north of 22nd Street, the main sector. The 22 Muni bus comes in from the Mission, and the 48 (from 24th/Mission) eventually reaches 22nd Street, although by an indirect route.

T-Muni Train on Third Street

Muni Station on 3rd Street near 20th Street

3rd Street near 22nd Street in Dogpatch

Serpentine Restaurant on 3rd Street near 22nd Street

3rd Street looking south toward 22nd Street in Dogpatch

Dogpatch Saloon on 22nd Street at 3rd

22nd Street near 3rd Street

Just For You Cafe on 22nd Street near 3rd - breakfast menu features homemade beignets

Piccino, pizza and coffee bar in Dogpatch

22nd Street in Dogpatch

22nd Street near Minnesota Street

Caltrain Station under the 280 Freeway in Dogpatch

House on Minnesota Street in Dogpatch

Minnesota Street between 22nd Street and 20th Street in Dogpatch

Entrance to Esprit Park in Dogpatch at Minnesota Street and 20th Street

Benches in Esprit Park in Dogpatch

Lawn in Esprit Park

Starting point for the 22-Fillmore Muni Bus line, at 20th Street between 3rd Street and Tennessee